Magnesium intake and risk of coronary heart disease among men
Magnesium intake and risk of coronary heart disease among men
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DOI:
10.1080/07315724.2004.10719344
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发表时间:
2004-02-01
影响因子:
3.5
通讯作者:
Hu, FB
中科院分区:
文献类型:
--
作者:
Al-Delaimy, WK;Rimm, EB;Hu, FB
Objective:. Our aim in this study was to assess the relationship between magnesium intake and risk of coronary heart disease (CHD) among men.Methods: A total of 39,633 men in the Health Professionals Follow-up Study who returned a dietary questionnaire in 1986 were followed up for 12 years. Intakes of magnesium, zinc and potassium and other nutrients were assessed in 1986, 1990 and 1994. Total CHD incidence (nonfatal myocardial infarction (MI) and fatal CHD) was ascertained by biennial questionnaire and mortality surveillance confirmed by medical record review. Standard CHD risk factors were recorded biennially.Results: During 12 years of follow-up (414,285 person-years), we documented 1,449 cases of total CHD (1,021 non-fatal MI cases, and 428 fatal CHD). The age-adjusted relative risk (RR) of developing CHD in the highest quintile (median intake = 457 mg/day) compared with the lowest quintile (median intake = 269 mg/day) was 0.73 (95% Cl 0.62-0.87, p for trend