A novel postcopulatory block of reproduction in white-footed mice.
A novel postcopulatory block of reproduction in white-footed mice.
复制标题
白足小鼠的一种新型交配后繁殖阻断。
DOI：
10.1095/biolreprod38.3.623
复制
发表时间：
1988
影响因子：
3.6
通讯作者：
Bronson,FH
中科院分区：
文献类型：
--
作者：
Haigh,GR;Cushing,BS;Bronson,FH
如果雌性白足鼠（Peromyscus leucopus）与雄性白足鼠配对，从断奶到150天大，如果雌性白足鼠或其气味也存在，则无法生育后代。本研究更清楚地描述了年轻雌性生殖周期的哪个阶段被老年雌性的化学信号所抑制。阴道开放的年龄和第一次发情会因老年女性的存在而延迟，但只有10天左右。雄性的出现抵消了这种延迟。因此，发育障碍的基础并不是青春期的延迟。老年女性的存在不影响第一次发情后30天内经历的发情周期的数量，也不影响尸检时发现的黄体的数量。年轻女性阴道中精子的存在表明它们正在交配。同样，在交配后2和3天检查胚胎显示正常的发育过程。然而，着床不会发生在年轻的女性已经暴露于一个成年女性。因此，阻滞要么发生在胚胎移植的最后阶段，要么发生在着床过程本身。
Female white-footed mice (Peromyscus leucopus) fail to produce offspring when paired with a male from weaning until 150 days of age if an adult female or her odor is also present. The present study delineates more clearly which stage of the young female’s reproductive cycle is inhibited by the chemosignal of the older female. Age at vaginal opening and first estrus are delayed by the presence of the older female, but only for about 10 days. The presence of a male counteracts this delay. Thus, the basis for the block is not a delay in puberty. The older female’s presence does not influence the number of estrous cycles experienced during the 30 days following first estrus, nor does it influence the number of corpora lutea found at autopsy. The presence of sperm in the vaginae of young females indicates that they were copulating. Likewise, examination of embryos 2 and 3 days after copulation reveals normal developmental progress. However, implantation does not occur in young females that have been exposed to an adult female. Thus, the block occurs either during the final stages of embryo transport or in relation to the implantation process itself.