ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli

ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli
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DOI:
10.1128/jb.183.15.4664-4667.2001
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发表时间:
2001-08-01
影响因子:
3.2
通讯作者:
Rensing, C
Rensing, C
中科院分区:
生物学3区
文献类型:
--
作者:
Grass, G;Fan, B;Rensing, C

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大肠杆菌zitB基因编码Zn(II)转运体,属于阳离子扩散促进剂家族。ZitB是由锌特异性诱导的。ZitB在质粒上的表达使被znta破坏的大肠杆菌细胞对锌的抵抗力增强,细胞中Zn-65的积累减少,表明ZitB介导了锌的外排。
The Escherichia coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family. ZitB is specifically induced by zinc. ZitB expression on a plasmid rendered zntA-disrupted E. coli cells more resistant to zinc, and the cells exhibited reduced accumulation of Zn-65, suggesting ZitB-mediated efflux of zinc.