Parametric effects of light acting via multiple photoreceptors contribute to circadian entrainment in Drosophila melanogaster.
Parametric effects of light acting via multiple photoreceptors contribute to circadian entrainment in Drosophila melanogaster.
复制标题
通过多个光感受器作用的光的参数效应有助于果蝇的昼夜节律夹带。
DOI：
10.1098/rspb.2023.0149
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发表时间：
2023-09-13
影响因子：
4.7
通讯作者：
Shafer, Orie Thomas
中科院分区：
文献类型：
--
作者：
Abhilash, Lakshman;Shafer, Orie Thomas
Circadian rhythms in physiology and behaviour have near 24 h periodicities that must adjust to the exact 24 h geophysical cycles on earth to ensure adaptive daily timing. Such adjustment is called entrainment. One major mode of entrainment is via the continuous modulation of circadian period by the prolonged presence of light. Although Drosophila melanogaster is a prominent insect model of chronobiology, there is little evidence for such continuous effects of light in the species. In this study, we demonstrate that prolonged light exposure at specific times of the day shapes the daily timing of activity in flies. We also establish that continuous UV- and blue-blocked light lengthens the circadian period of Drosophila and provide evidence that this is produced by the combined action of multiple photoreceptors which, includes the cell-autonomous photoreceptor cryptochrome. Finally, we introduce ramped light cycles as an entrainment paradigm that produces light entrainment that lacks the large light-driven startle responses typically displayed by flies and requires multiple days for entrainment to shifted cycles. These features are reminiscent of entrainment in mammalian models systems and make possible new experimental approaches to understanding the mechanisms underlying entrainment in the fly.
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影响因子：
4.6
作者：
Nguyen ND;Matsuura T;Kato Y;Watanabe H
通讯作者：
Watanabe H
影响因子：
3.5
作者：
Leise, Tanya L.
通讯作者：
Leise, Tanya L.
影响因子：
--
作者：
Leise TL
通讯作者：
Leise TL
影响因子：
3.5
作者：
Kistenpfennig, Christa;Nakayama, Mayumi;Yoshii, Taishi
通讯作者：
Yoshii, Taishi
影响因子：
9.2
作者：
Lee, SJ;Montell, C
通讯作者：
Montell, C