Epidemiological association between cigarette smoking and primary open-angle glaucoma: a meta-analysis
Epidemiological association between cigarette smoking and primary open-angle glaucoma: a meta-analysis
复制标题
DOI：
10.1016/j.puhe.2003.09.009
复制
发表时间：
2004-06-01
期刊：
影响因子：
5.2
通讯作者：
Peponis, V
中科院分区：
文献类型：
--
作者：
Bonovas, S;Filioussi, K;Peponis, V
客观的。吸烟作为原发性开角型青光眼（POAG）的危险因素仍然存在争议。本研究的目的是通过对同行评审文献中发表的有关该主题的研究进行详细的荟萃分析来检验这种关联。方法。对 2002 年 12 月 31 日发表的文章进行了全面检索，对每项研究进行了回顾，并提取了数据。在荟萃分析之前，对研究的发表偏倚和异质性进行了评估。结果。我们的分析基于七份报告。我们没有发现研究之间存在发表偏倚或异质性的证据。固定效应模型的总结比值比对于当前吸烟者为 1.37 (95% CI: 1.00-1.87)，对于过去吸烟者为 1.03 (95% CI: 0.77-1.38)。结论。我们的荟萃分析结果表明，当前吸烟者患 POAG 的风险显着增加。应努力加强反对吸烟的运动，将 POAG 风险增加添加到众所周知的反对吸烟的论点中。 (C) 2003 年皇家公共卫生研究所。由爱思唯尔有限公司出版。保留所有权利。
Objective. The rote of cigarette smoking as a risk factor for primary open-angle glaucoma (POAG) remains controversial. The aim of this study was to examine this association by conducting a detailed meta-analysis of studies published in peer-reviewed literature on the subject.Methods. A comprehensive search for articles published up 31 December 2002 was performed, reviews of each study were conducted, and data were abstracted. Prior to meta-analysis, the studies were evaluated for publication bias and heterogeneity.Results. Our analysis was based on seven reports. We found no evidence of publication bias or heterogeneity among the studies. The summary odds ratios from a fixed-effects model were 1.37 (95% CI: 1.00-1.87) for current smokers and 1.03 (95% CI: 0.77-1.38) for past smokers.Conclusions. Our meta-analysis results suggest that current smokers are at significantly increased risk of developing POAG. Efforts should be directed towards augmenting the campaign against smoking by adding the increased risk of POAG to the better-known arguments against smoking. (C) 2003 The Royal Institute of Public Health. Published by Elsevier Ltd. All rights reserved.