Hodgkin lymphoma-associated hemophagocytic syndrome:: A disorder strongly correlated with Epstein-Barr virus
Hodgkin lymphoma-associated hemophagocytic syndrome:: A disorder strongly correlated with Epstein-Barr virus
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DOI：
10.1086/590152
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发表时间：
2008-08-15
影响因子：
11.8
通讯作者：
Larroche, Claire
中科院分区：
文献类型：
--
作者：
Menard, Fanny;Besson, Caroline;Larroche, Claire
对34例霍奇金淋巴瘤相关噬血细胞综合征患者的回顾性研究使我们将这种相关性定义为一种特定的疾病。其特征是男性占优势（男女性别比为3.3：1），免疫缺陷样组织学特征（淋巴细胞耗竭，45%的病例;混合细胞型霍奇金淋巴瘤亚型，40%），以及与EB病毒密切相关（94%）。
The retrospective study of 34 patients with Hodgkin lymphoma-associated hemophagocytic syndrome led us to define this association as a specific disorder. Its characteristics are male predominance (male-to-female sex ratio, 3.3:1), immunodeficiency-like histological features (lymphocyte depletion, 45% of cases; mixed cellularity Hodgkin lymphoma subtype, 40%), and strong association with Epstein-Barr virus (94%).