3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.
3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.
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3-氨基-2,4-BNA：具有N3-->P5氨基磷酸酯键的新型桥接核酸。
DOI：
10.1039/b105640a
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发表时间：
2001
影响因子：
4.9
通讯作者：
T. Imanishi
中科院分区：
文献类型：
--
作者：
S. Obika;M. Onoda;K. Morita;J. Andoh;M. Koizumi;T. Imanishi
成功合成了含有3 '-氨基-2'，4 '-BNA单元的新型寡核苷酸类似物，它们表现出与BNA本身一样的上级双链体和三链体形成能力，并且沿着具有显着的酶稳定性。
Novel oligonucleotide analogues, containing a 3'-amino-2',4'-BNA unit, were successfully synthesized, and they showed superior duplex and triplex forming ability as well as BNA itself, along with remarkable enzymatic stability.