TEMPO promoted direct multi-functionalization of terminal alkynes with 2-oxindoles/benzofuran-2(3H)-one
TEMPO promoted direct multi-functionalization of terminal alkynes with 2-oxindoles/benzofuran-2(3H)-one
复制标题
TEMPO 促进末端炔烃与 2-oxindoles/苯并呋喃-2(3H)-one 的直接多功能化
DOI：
10.1039/c8ob01380b
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发表时间：
2018
影响因子：
3.2
通讯作者：
Liu Li
中科院分区：
文献类型：
--
作者：
Liu Qi;Liu Jie-Jie;Cheng Liang;Wang Dong;Liu Li
Highly selective and catalyst-free tandem multi-functionalization of terminal alkynes was developed with 2-oxindoles and benzo-furan-2(3H)-one using TEMPO both as a radical promoter and a trapping reagent. This work expands the scope of the radical-cascade addition/trapping process of alkynes for the effective construction of various β-oxyl carbonyls in moderate to good yields.
