Observations on parent/family factors that may influence the duration of untreated psychosis among African American first-episode schizophrenia-spectrum patients
Observations on parent/family factors that may influence the duration of untreated psychosis among African American first-episode schizophrenia-spectrum patients
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DOI：
10.1016/j.schres.2003.09.001
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发表时间：
2004-06-01
影响因子：
4.5
通讯作者：
Walker, EF
中科院分区：
文献类型：
--
作者：
Compton, MT;Kaslow, NJ;Walker, EF
精神病未治疗持续时间（DUP）是精神分裂症二级预防研究中的一个重要概念。尽管迄今为止的研究结果喜忧参半，但几项研究已证明治疗延迟的持续时间与各种临床和心理社会结局之间存在负相关。需要进行研究以更好地了解DUP的多因素决定因素，家庭对DUP的影响可能是重要的预测因素。作者介绍了6名非洲裔美国人首发患者的10名父母/兄弟姐妹的基本描述性统计和病史。家庭成员（5名母亲、2名父亲、1名继父和2名兄弟姐妹）报告的平均DUP为59.5周（范围2-234周）。家庭成员对精神分裂症的知识水平不一定对治疗延迟的时间有重大影响。在这个小样本的亲属，早期精神病症状往往归因于抑郁症，缺乏动力或关系的压力。家庭成员寻求帮助的决定往往是在出现无法忍受的精神病症状或社会破坏性行为后才得以巩固。家庭成员对DUP的报告一致性低，并认为获得精神科服务的障碍是意外的发现。这些初步观察结果可能有助于产生进一步研究的假设，旨在阐明精神分裂症早期治疗延迟的决定因素，特别是在非洲裔美国人人群中。(C)2003 Elsevier B. V.保留所有权利。
The duration of untreated psychosis (DUP) is a concept of importance in schizophrenia research from the perspective of secondary prevention. Although findings to date are mixed, several studies have demonstrated an inverse association between the duration of treatment delay and a variety of clinical and psychosocial outcomes. Research is needed to better understand the multifactorial determinants of the DUP and family-level influences on the DUP may prove to be important predictors. The authors present basic descriptive statistics and case histories of 10 parents/siblings of 6 African American first-episode patients. The mean DUP reported by the family members (five mothers, two fathers, one stepfather and two siblings) was 59.5 weeks (range 2-234). Family members' levels of knowledge of schizophrenia may not necessarily have a major impact upon the length of treatment delays. Among this small sample of relatives, early psychotic symptoms were often attributed to depression, lack of motivation or relational stressors. Family members' decisions to seek help often were solidified only after the emergence of unbearable psychotic symptoms or socially disruptive behaviors. Low concordance among family members' reports of the DUP and perceived barriers to accessing psychiatric services were unexpected findings. These preliminary observations may serve to generate hypotheses for further research that aims to elucidate the determinants of treatment delays in the early course of schizophrenia, especially among African American populations. (C) 2003 Elsevier B.V. All rights reserved.