Neural correlates of personality dimensions and affective measures during the anticipation of emotional stimuli
Neural correlates of personality dimensions and affective measures during the anticipation of emotional stimuli
复制标题
DOI：
10.1007/s11682-011-9114-7
复制
发表时间：
2011-06-01
影响因子：
3.2
通讯作者：
Herwig, Uwe
中科院分区：
文献类型：
--
作者：
Bruehl, Annette Beatrix;Viebke, Marie-Caroline;Herwig, Uwe
神经质和外向性是影响个体情绪加工的两种人格维度。神经质与抑郁和焦虑障碍相关，暗示了一个共同的神经生物学基础。外向性与焦虑和抑郁呈负相关。本研究利用功能磁共振成像技术研究了健康成人受试者在情绪刺激的暗示预期过程中，人格与抑郁和焦虑的神经关联。尤其是前额叶和其他皮质区域以及丘脑的分布与外向性有关。顶枕区、颞区和皮层下尾状核与神经质和情感测量相关。神经质相关区域与焦虑和抑郁部分交叉相关，反之亦然。与外向相关的活动与其他测量没有相关性。与神经质和情感测量相比，外向性的神经关联符合人格维度的不同神经生物学基础概念，并指向情感障碍的易感性。
Neuroticism and extraversion are proposed personality dimensions for individual emotion processing. Neuroticism is correlated with depression and anxiety disorders, implicating a common neurobiological basis. Extraversion is rather inversely correlated with anxiety and depression. We examined neural correlates of personality in relation to depressiveness and anxiety in healthy adult subjects with functional magnetic resonance imaging during the cued anticipation of emotional stimuli. Distributed particularly prefrontal but also other cortical regions and the thalamus were associated with extraversion. Parieto-occipital and temporal regions and subcortically the caudate were correlated with neuroticism and affective measures. Neuroticism-related regions were partially cross-correlated with anxiety and depression and vice versa. Extraversion-related activity was not correlated with the other measures. The neural correlates of extraversion compared with those of neuroticism and affective measures fit with concepts of different neurobiological bases of the personality dimensions and point at predispositions for affective disorders.