Calcium Metabolism and Correcting Calcium Deficiencies
Calcium Metabolism and Correcting Calcium Deficiencies
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DOI：
10.1016/j.ecl.2012.04.019
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发表时间：
2012-09-01
影响因子：
4.5
通讯作者：
Emkey, Gregory R.
中科院分区：
文献类型：
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作者：
Emkey, Ronald D.;Emkey, Gregory R.
钙是人体内最丰富的阳离子，其中约99%存在于骨骼中，有助于其刚性和强度。骨骼还可以作为钙的储存库，因为它在多种生理和生化过程中发挥作用。本文旨在通过对这些过程的吸收机制和影响因素的深入了解，使人们能够更好地了解个体的钙需求，为纠正钙缺乏提供理论依据。概述了钙的需要量和推荐的剂量方案，并讨论了各种钙制剂和钙治疗的潜在毒性。
Calcium is the most abundant cation in the human body, of which approximately 99% occurs in bone, contributing to its rigidity and strength. Bone also functions as a reservoir of Ca for its role in multiple physiologic and biochemical processes. This article aims to provide a thorough understanding of the absorptive mechanisms and factors affecting these processes to enable one to better appreciate an individual's Ca needs, and to provide a rationale for correcting Ca deficiencies. An overview of Ca requirements and suggested dosing regimens is presented, with discussion of various Ca preparations and potential toxicities of Ca treatment.