Occupation and lung cancer mortality in a nationally representative U.S. Cohort: The National Health Interview Survey (NHIS).
Occupation and lung cancer mortality in a nationally representative U.S. Cohort: The National Health Interview Survey (NHIS).
复制标题
具有全国代表性的美国队列中的职业和肺癌死亡率：国家健康访谈调查 (NHIS)。
DOI：
10.1097/01.jom.0000225137.19863.4e
复制
发表时间：
2006
影响因子：
3.2
通讯作者：
Pitman,Terry
中科院分区：
文献类型：
--
作者：
Lee,DavidJ;Fleming,LoraE;Leblanc,WilliamG;Arheart,KristopherL;Chung-Bridges,Katherine;Christ,SharonL;Caban,AlbertoJ;Pitman,Terry
目的：本研究的目的是评估按职业划分的具有全国代表性的美国工人样本中肺癌死亡的风险。方法：全国死亡指数联动确定了参与 1987 年、1988 年和 1990-1994 年全国健康访谈调查的 143,863 名工人中的 1812 例肺癌死亡。结果：当前和以前的吸烟状况可预测肺癌死亡率（风险比 [HR]= 15.1 和分别为 3.8）。根据年龄和吸烟调整的肺癌死亡率风险显着较高的职业包括供暖/空气/制冷机械师（HR = 3.0）；未指定机械师和修理工（HR= 2.8）；财务记录处理职业（HR=1.8）；货运、库存和材料处理人员（HR= 1.5）；和精密生产职业（HR=1.4）。结论：尽管烟草使用仍然是肺癌死亡的最重要的单一危险因素，但也应有针对性地减少肺癌致癌物的职业暴露，以进一步减轻肺癌负担。
Objective:The objective of this study was to assess the risk of lung cancer mortality in a nationally representative sample of US workers by occupation.Methods:National Death Index linkage identified 1812 lung cancer deaths among 143,863 workers who participated in the 1987, 1988, and 1990–1994 National Health Interview Surveys.Results:Current and former smoking status was predictive of lung cancer mortality (hazard ratio [HR]= 15.1 and 3.8, respectively). Occupations with significantly higher risk for age-and smoking-adjusted lung cancer mortality included heating/air/refrigeration mechanics (HR= 3.0); not specified mechanics and repairers (HR= 2.8); financial records processing occupations (HR= 1.8); freight, stock, and materials handlers (HR= 1.5); and precision production occupations (HR= 1.4).Conclusion:Although tobacco use continues to be the single most important risk factor for lung cancer mortality, occupational exposure to lung carcinogens should be targeted as well to further reduce the burden of lung cancer.