What Are We Treating with Chronic Opioid Therapy?
What Are We Treating with Chronic Opioid Therapy?
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我们用慢性阿片类药物治疗治疗什么？
DOI：
10.1007/s11926-012-0311-1
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发表时间：
2013
影响因子：
5
通讯作者：
J. Ballantyne
中科院分区：
文献类型：
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作者：
D. Krashin;M. Sullivan;J. Ballantyne
最近，长期服用阿片类药物治疗疼痛的患者数量有所增加，但并未在减轻症状和改善功能方面产生预期的益处。慢性疼痛患者通常最初对阿片类药物反应良好，但经常使用会带来不良的心理和身体影响。患有严重精神合并症和物质使用问题的患者更有可能继续服用阿片类药物并接受更高剂量。在纤维肌痛和骨关节炎等常见风湿病中，阿片类药物治疗效果有限，因为缺乏疗效且副作用突出。慢性阿片类药物治疗可能更有效地被视为一种舒适护理形式，专为那些已经用尽其他治疗方法且有望康复的患者保留。
The recent increase in the number of patients taking opioids chronically for pain has not yielded the expected benefits in reduction of symptoms and improved function. Chronic pain patients typically respond well initially to opioid medications, but regular use is associated with adverse psychological and physical effects. Patients with significant psychiatric comorbidity and substance use issues are more likely to stay on opioids and to receive higher doses. In the common rheumatological conditions of fibromyalgia and osteoarthritis, opioid treatment is of limited benefit because of lack of efficacy and prominent side effects. Chronic opioid therapy may be more usefully regarded as a form of comfort care, reserved for those patients who have exhausted other treatments and prospects of recovery.
DOI：
10.1016/j.jpain.2008.10.008
发表时间：
2009-02
期刊：
The journal of pain
影响因子：
--
作者：
Chou R;Fanciullo GJ;Fine PG;Adler JA;Ballantyne JC;Davies P;Donovan MI;Fishbain DA;Foley KM;Fudin J;Gilson AM;Kelter A;Mauskop A;O'Connor PG;Passik SD;Pasternak GW;Portenoy RK;Rich BA;Roberts RG;Todd KH;Miaskowski C;American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
通讯作者：
American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel