Visual imagery of famous faces: Effects of memory and attention revealed by fMRI
Visual imagery of famous faces: Effects of memory and attention revealed by fMRI
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DOI：
10.1006/nimg.2002.1330
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发表时间：
2002-12-01
期刊：
影响因子：
5.7
通讯作者：
Ungerleider, LG
中科院分区：
文献类型：
--
作者：
Ishai, A;Haxby, JV;Ungerleider, LG
复杂的图像信息可以作为心理视觉图像从记忆中再现和检索。脑功能成像研究表明，视觉感知和视觉图像具有共同的神经基质。然而，调节心理图像生成的记忆类型（短期或长期）在此之前并没有被提及。本研究的目的是探讨短期和长期记忆（STM和LTM）产生的潜在图像的神经相关。我们使用名人面孔来定位感知过程中的视觉反应，并比较STM（受试者在图像任务前记忆名人的特定图片）和LTM（受试者在实验过程中想象名人面孔而不看到特定图片）产生视觉图像时的反应。我们发现，对名人面孔的视觉感知激活了枕下回、外侧梭状回、颞上沟和杏仁核。这些面部选择区域的一小部分在成像过程中被激活。此外，名人面孔的视觉图像激活了由双侧胼胝体、海马体、楔前叶、顶叶内沟（IPS）和额下回（IFG）组成的区域网络。在所有这些区域中，STM生成的图像比LTM生成的图像激发了更多的激活。无论记忆类型如何，将注意力集中在想象中的面部特征上（例如，眼睛、嘴唇或鼻子）会导致右侧IPS和右侧IFG的激活增加。我们的研究结果表明，记忆和注意力在一代面孔的不同影响。
Complex pictorial information can be represented and retrieved from memory as mental visual images. Functional brain imaging studies have shown that visual perception and visual imagery share common neural substrates. The type of memory (short- or long-term) that mediates the generation of mental images, however, has not been addressed previously. The purpose of this study was to investigate the neural correlates underlying imagery generated from short- and long-term memory (STM and LTM). We used famous faces to localize the visual response during perception and to compare the responses during visual imagery generated from STM (subjects memorized specific pictures of celebrities before the imagery task) and imagery from LTM (subjects imagined famous faces without seeing specific pictures during the experimental session). We found that visual perception of famous faces activated the inferior occipital gyri, lateral fusiform gyri, the superior temporal sulcus, and the amygdala. Small subsets of these face-selective regions were activated during imagery. Additionally, visual imagery of famous faces activated a network of regions composed of bilateral calcarine, hippocampus, precuneus, intraparietal sulcus (IPS), and the inferior frontal gyrus (IFG). In all these regions, imagery generated from STM evoked more activation than imagery from LTM. Regardless of memory type, focusing attention on features of the imagined faces (e.g., eyes, lips, or nose) resulted in increased activation in the right IPS and right IFG. Our results suggest differential effects of memory and attention during the generation faces.