Animal- and herd-level risk factors for leptospiral seropositivity among sows in the Mekong delta, Vietnam
Animal- and herd-level risk factors for leptospiral seropositivity among sows in the Mekong delta, Vietnam
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DOI：
10.1016/s0167-5877(01)00263-x
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发表时间：
2002-03-14
影响因子：
2.6
通讯作者：
Magnusson, U
中科院分区：
文献类型：
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作者：
Boqvist, S;Chau, BL;Magnusson, U
1998年，在越南湄公河三角洲共收集了424头母猪的血清。其中，283头母猪来自19个村的151个小型家庭农场，141头来自7个大型国营农场。对血清进行显微镜凝集试验（MAT），以检测13种钩端螺旋体血清型的抗体。滴度大于或等于1：100和>1：400的总体钩端螺旋体血清阳性率分别为73%和29%，并且在小规模农场高于大规模农场（P = 0.001）。最高的血清阳性率记录为问号钩端螺旋体血清型（SV）布拉迪斯拉发（52%）。在小规模养殖场，黄疸出血型问号钩端螺旋体（P = 0.04）和钩端螺旋体（P = 0.05）的流行率较高。通过问卷调查收集流行病学信息（在个体动物和动物水平）。使用logistic多元回归分析数据。在动物水平上，对南方型钩端螺旋体和秋季型钩端螺旋体血清学呈阳性的母猪与邻近围栏中的母猪的直接接触较少（比值比（OR）分别为0.3和0.4），对南方型钩端螺旋体血清学呈阴性的母猪与邻近围栏中的母猪的直接接触较少（OR分别为0.3和0.4）。布拉第斯拉瓦型问号线虫的年龄较低（血清阳性的OR = 0.1）。此外，母猪血清学阳性的L。如果不是在农场出生（作为后备母猪被引入），则问号鼠黄疸出血型（SV）的感染几率较高（OR = 5.8），爪哇型血清学阳性的畜群与农场未采取措施控制当地啮齿动物种群有关（OR = 7.8）。波莫纳血清型也与人工授精（AI）的使用，而不是自然繁殖服务（OR = 11.2）。这些结果表明，住房和管理可能会影响钩端螺旋体感染的血清阳性率在猪。(C)2002爱思唯尔科技有限公司。保留所有权利。
In 1998, a total of 424 sows had sera collected in the Mekong delta in Vietnam. Of these, 283 sows were from 151 small-scale family farms in 19 villages, and 141 from seven large-scale state farms. The sera were subjected to the microscopic agglutination test (MAT) for antibodies to 13 Leptospira serovars. The overall leptospiral seroprevalence for titres greater than or equal to1:100 and >1:400, was 73 and 29%, respectively, and was higher (P = 0.001) at small- than at large-scale farms. The highest seroprevalence was recorded for Leptospira interrogans serovar (sv) bratislava (52%). At small-scale farms, higher prevalences were found to serovars L interrogans sv icterohaemorrhagiae (P = 0.04) and L. interrogans sv pomona (P = 0.02).Epidemiological information (at the individual-animal and herd-levels) was collected with a questionnaire. The data were analysed using logistic multiple regression. At the animal-level, sows seropositive for L interrogans sv australis and sv autumnalis had less direct contact with sows in neighbouring pens (odds ratio (OR) = 0.3 and 0.4, respectively) and sows seronegative for L. interrogans sv bratislava were of lower age (OR = 0.1 for seropositivity). Also, sows seropositive for L. interrogans sv icterohaemorrhagiae had higher odds (OR = 5.8) if they had not been born on the farm (had been introduced to it as gilts).Herds seropositive for sv javanica showed association with farms not taking measures to control the local rodent population (OR = 7.8). Serovar pomona was also linked to the use of artificial insemination (AI), as opposed to natural-breeding services (OR = 11.2).These results indicate that housing and management could affect the seroprevalence of Leptospira infection in pigs. (C) 2002 Elsevier Science B.V. All rights reserved.