Coronary intervention for persistent occlusion after myocardial infarction
Coronary intervention for persistent occlusion after myocardial infarction
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DOI：
10.1056/nejmoa066139
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发表时间：
2006-12-07
影响因子：
158.5
通讯作者：
Knatterud, Genell L.
中科院分区：
文献类型：
--
作者：
Hochman, Judith S.;Lamas, Gervasio A.;Knatterud, Genell L.
背景：目前尚不清楚在目前可接受的心肌挽救期过后，稳定的、高风险的患者是否应该在接受最佳药物治疗的同时接受经皮冠状动脉介入治疗(PCI)，以降低后续事件的风险。方法：我们进行了一项随机研究，涉及2166名心肌梗死后3-28天完全闭塞的稳定患者，他们符合高危标准(射血分数)。
BACKGROUND:It is unclear whether stable, high-risk patients with persistent total occlusion of the infarct-related coronary artery identified after the currently accepted period for myocardial salvage has passed should undergo percutaneous coronary intervention (PCI) in addition to receiving optimal medical therapy to reduce the risk of subsequent events.METHODS:We conducted a randomized study involving 2166 stable patients who had total occlusion of the infarct-related artery 3 to 28 days after myocardial infarction and who met a high-risk criterion (an ejection fraction of