First examination of sterols in the marine dinoflagellate genus Vulcanodinium
First examination of sterols in the marine dinoflagellate genus Vulcanodinium
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DOI：
10.1111/jeu.12863
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发表时间：
2021-06
影响因子：
2.2
通讯作者：
Stephanie L. Vandergrift;Lindsey C. Elkins;C. Alves-de-Souza;Jeffrey D. Leblond
中科院分区：
文献类型：
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作者：
Stephanie L. Vandergrift;Lindsey C. Elkins;C. Alves-de-Souza;Jeffrey D. Leblond
Vulcanoddium是一种与生态相关的甲鞭毛虫属，因为它能产生被称为Pinnatoxins的神经毒素。在这里，我们提出了第一次检查的甾醇的葡萄糖菌分离物。甾醇是一种环状脂类，有助于维持细胞膜的刚性，而Dinophyceae因其产生多种甾醇的能力而被广泛研究，其中许多具有化学分类作用。我们已经确定该弧菌产生一组主要的甾醇，即胆固醇、地诺甾醇、4-二甲基-5-α-α-Cholest-22E-en-3-β-ol和4-α，24-二甲基-5-α-Cholestan-3-β-ol，这是Dinophyceae常见的。然而，这与系统发育关系最近的Scrippsiella属和Periddium属的那些研究成员显示出显著的差异。包括在这些差异中的是红色假单胞菌产生的地诺甾醇的百分比要低得多，地诺甾醇是一种饱和形式的地诺甾醇。
Vulcanodinium is an ecologically relevant dinoflagellate genus due to its production of neurotoxins known as pinnatoxins. We present here the first examination of the sterols of a Vulcanodinium rugosum isolate. Sterols are ringed lipids that assist in maintaining rigidity of cellular membranes, and the Dinophyceae are well‐studied for their ability to produce a diverse array of sterols, many of which have chemotaxonomic utility. We have determined that V. rugosum produces a set of major sterols, namely cholesterol, dinosterol, 4α,24‐dimethyl‐5α‐cholest‐22E‐en‐3β‐ol, and 4α,24‐dimethyl‐5α‐cholestan‐3β‐ol, common to the Dinophyceae. However, this displayed marked differences from those studied members of the genera Scrippsiella and Peridinium, the closest phylogenetic relatives. Included in these differences is production by V. rugosum of a much lower percentage of dinostanol, a saturated form of dinosterol.