Influence of Implant Neck Design on Bone Formation under Mechanical Repetitive Loading: Histomorphometric and Microcomupted Tomographic Studies in Rabbit Tibiae.
Influence of Implant Neck Design on Bone Formation under Mechanical Repetitive Loading: Histomorphometric and Microcomupted Tomographic Studies in Rabbit Tibiae.
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种植体颈部设计对机械重复负载下骨形成的影响：兔胫骨的组织形态测量和微计算机断层扫描研究。
DOI：
10.1097/id.0000000000000384
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Sawase T.
中科院分区：
文献类型：
--
作者：
Yasutake M†;Kuroshima S†;Ishimoto T;Nakano T;Sawase T.
目的：本研究的目的是探讨种植体颈部设计对骨整合和骨形成的原始概念的影响，当施加机械重复负荷时，通过骨整合implants.Materials和Methods：28个阳极氧化Ti-6Al-4V合金种植体，种植体颈部有+60或-60凹槽，被放置在14只家兔的胫骨近端干骺端。14个种植体在种植体植入后12周接受沿种植体长轴沿着的机械重复载荷8周。其余14个种植体未接受载荷。组织形态计量学和显微计算机断层扫描分析，然后performed.Results：没有观察到颈部设计的影响，没有机械负荷，而周围的+60槽骨整合与机械负荷上调。计算出的载荷对种植体颈部周围骨结构的影响与+60槽相比，-60槽在机械loaded.Conclusions：这些研究结果表明，建立骨整合和骨形成周围的种植体颈部与+60槽是上级的负载条件下与-60槽。
Purpose:The aim of this study was to investigate effects of implant neck design on the original concept of osseointegration and bone formation when applying mechanical repetitive loading by bone-integrated implants.Materials and Methods:Twenty-eight anodized Ti-6Al-4V alloy implants with+ 60 or− 60 grooves in the implant neck were placed in the proximal tibial metaphysis of 14 rabbits. Fourteen implants received mechanical repetitive loading along the long axis of the implant for 8 weeks at 12 weeks after implant placement. The remaining 14 implants received no loading. Histomorphometric and microcomputed tomographic analyses were then performed.Results:No effect of neck design was observed without mechanical loading, whereas osseointegration around the+ 60 grooves was upregulated with mechanical loading. Calculated load effects on bone structure around the implant neck with+ 60 grooves were larger when compared with the− 60 grooves under mechanical loading.Conclusions:These findings indicate that the establishment of osseointegration and bone formation around the implant neck with+ 60 grooves is superior to those with− 60 grooves under loaded conditions.