Variations in vital signs at the end of life in non-cancer patients: a retrospective study
Variations in vital signs at the end of life in non-cancer patients: a retrospective study
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DOI：
10.21037/apm-20-1054
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发表时间：
2020-09-01
影响因子：
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通讯作者：
Hamano, Jun
中科院分区：
文献类型：
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作者：
Hosoi, Takahiro;Ozone, Sachiko;Hamano, Jun
背景资料：即将死亡的预测是重要的，提供适当的临终关怀，但是，有限的信息，目前可在非癌症患者即将死亡的迹象。此外，虽然生命体征常规测量在临床实践中，在非癌症患者的死亡阶段的生命体征的变化还没有被阐明details.Methods：我们在此进行了一项回顾性研究，以澄清在非癌症患者死亡前的生命体征的变化。对2017年4月至2018年4月期间在日本一家医院死亡的非癌症患者进行了检查。分析死亡前长达7天的生命体征，绘制每12小时的平均值。我们将数据分为两个时期：从第-7天到第-4天和从第-3天到死亡。我们使用线性混合模型在两个时期，和t检验进行评估是否跨时间变量的线的梯度显着不同zero.Results：从47个非癌症患者的数据进行了分析。收缩压（P
Background: The prediction of impending death is important for providing appropriate end-of-life care; however, limited information is currently available on the signs of impending death in non-cancer patients. Furthermore, although vital signs are routinely measured in clinical practice, changes in vital signs in the dying phase in non-cancer patients have not yet been elucidated in detail.Methods: We herein conducted a retrospective study to clarify changes in vital signs before death in non-cancer patients. Non-cancer patients who died in a hospital in Japan between April 2017 and April 2018 were examined. Vital signs for up to seven days before death were analyzed, with the average value of each vital sign approximately every twelve hours being plotted. We divided data into two periods: from days -7 to -4 and from day -3 to death. We used a linear mixed model in the two periods, and t-tests were performed to assess whether the gradient of the line across the time variable significantly differed from zero.Results: Data from 47 non-cancer patients were analyzed. Systolic blood pressure (P