The value of screening for sexually transmitted diseases in an HIV clinic
The value of screening for sexually transmitted diseases in an HIV clinic
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DOI：
10.1097/00126334-200308150-00014
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发表时间：
2003-08-15
影响因子：
3.6
通讯作者：
Besch, CL
中科院分区：
文献类型：
--
作者：
Farley, TA;Cohen, DA;Besch, CL
由于细菌性传播疾病(STD)促进了艾滋病毒的传播，因此在艾滋病毒感染者中筛查和治疗STD应防止艾滋病毒向伴侣传播。在艾滋病毒诊所广泛建立淋病和衣原体感染筛查计划之前，了解这些感染的流行情况是有用的。这项研究分析了新奥尔良一家艾滋病毒诊所基于尿液的淋病和衣原体筛查项目的结果，并将阳性率与当地社区的流行率进行了比较。在HIV门诊筛查的人中，1.7%(46/2629)患有淋病，2.1%(56/2629)患有衣原体感染。在18-29岁人群中，HIV诊所的淋病检测阳性率与社会人口学相似的社区样本中的人群相似(3.1%对2.4%，调整后优势比1.6，P=0.11)，而衣原体感染检测阳性率较低(5.4%对10.5%，调整后优势比0.6，P<；0.01)。根据之前发表的数学模型，据估计，在艾滋病毒诊所治疗所有46例淋病和56例衣原体感染可能避免了9例性伴侣感染艾滋病毒，并在未来节省的医疗费用远远超过筛查费用。HIV诊所应考虑进行淋病和衣原体感染的常规筛查。
Because bacterial sexually transmitted diseases (STDs) facilitate HIV transmission, screening for and treatment of STDs among HIV-infected persons should prevent HIV spread to partners. Before screening programs for gonorrhea and Chlamydia infection should be widely established in HIV clinics, it is useful to know the prevalence of these infections. This study analyzed the results of a urine-based screening program for gonorrhea and Chlamydia in a New Orleans HIV clinic and compared the positivity rates to the prevalence in the local community. Among persons screened in the HIV clinic, 1.7% (46/2629) had gonorrhea and 2.1% (56/2629) had Chlamydia infection. Among persons aged 18-29 years, the test positivity for gonorrhea was similar in the HIV clinic to that of persons in sociodemographically similar community samples (3.1 versus 2.4%, adjusted odds ratio 1.6, P = 0.11) and the test positivity for Chlamydia infection was lower (5.4% versus 10.5%, adjusted odds ratio 0.6, P < 0.01). Based on a previously published mathematical model, it was estimated that treatment of all 46 gonorrhea and 56 Chlamydia infections in the HIV clinic may have averted 9 HIV infections among sex partners and saved far more in future medical costs than the cost of the screening. Routine screening for gonorrhea and Chlamydia infection should be considered in HIV clinics.