Short-term effects of real-time personal PM2.5 exposure on ambulatory blood pressure: A panel study in young adults.
Short-term effects of real-time personal PM2.5 exposure on ambulatory blood pressure: A panel study in young adults.
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DOI：
10.1016/j.scitotenv.2019.134079
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发表时间：
2019-12
期刊：
影响因子：
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通讯作者：
M. Ren;Huanhuan Zhang;T. Benmarhnia;B. Jalaludin;Haotian Dong;K. Wu;Qiong Wang;Cunrui Huang
中科院分区：
文献类型：
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作者：
M. Ren;Huanhuan Zhang;T. Benmarhnia;B. Jalaludin;Haotian Dong;K. Wu;Qiong Wang;Cunrui Huang
研究背景短期暴露于PM2.5已被证明与血压的变化有关。然而，大多数证据都是基于固定站的PM2.5测量和定期测量的静息血压。ObjectivesTo评估实时个人PM2.5暴露对动态血压的短期每日和每小时影响，并与固定站PM2.5暴露的影响进行比较。在北京市中心城区和郊区各招募37名青年人，连续3天测量个人每小时PM2. 5和动态收缩压（SBP）、舒张压（DBP）。每小时的PM2.5浓度也是从广东省环境监测中心最近的监测站获得的。结果在研究期间，个人PM2.5暴露平均浓度为60.30 ± 52.14 μg/m3，固定站PM2.5暴露平均浓度为36.77 ± 21.52 μg/m3。个人PM2.5暴露和固定站暴露在过去1至3天的平均值降低血压。在白天，个人PM2.5的1天移动平均值增加10 μg/m3，SBP和DBP分别降低0.54 mmHg（95% CI：-1.03，-0.05）和0.22 mmHg（95% CI：-0.59，0.15）。当使用来自固定站点的PM2.5暴露时，SBP和DBP分别降低0.95 mmHg（95% CI：-1.82，-0.07）和0.74 mmHg（95% CI：-1.46，-0.03）。分层分析显示，在中心城区和之间的muslims.ConclusionsBoth个人PM2.5暴露和暴露从固定站平均在过去的1至3天降低血压的影响。在中心城区和男性中发现了更强的影响。
BackgroundShort-term exposure to PM2.5has been shown to be associated with changes in blood pressure. However, most of the evidence is based on PM2.5measurements from fixed stations and resting blood pressure measured at a regular time.ObjectivesTo evaluate the short-term daily and hourly effects of real-time personal PM2.5exposure on ambulatory blood pressure, and to compare the effects with those of PM2.5exposure from fixed stations.MethodsBetween April 2017 and December 2017, 37 young adults were recruited in a panel study from a central urban area and a suburban area, to measure personal hourly PM2.5and ambulatory systolic blood pressure (SBP) as well as diastolic blood pressure (DBP) for three consecutive days. Hourly PM2.5concentrations were also obtained from the nearest monitoring station operated by Guangdong Environmental Monitoring Center. Generalized additive mixed model was employed to evaluate the effects of PM2.5on ambulatory blood pressure.ResultsDuring the study period, the mean concentration of personal PM2.5exposure was 60.30 ± 52.14 μg/m3, while the value of PM2.5from fixed stations was 36.77 ± 21.52 μg/m3. Both personal PM2.5exposure and exposure from fixed stations averaged over the previous 1 to 3 days decreased blood pressure. During daytime, a 10 μg/m3increase in 1-day moving average of personal PM2.5was associated with a 0.54 mmHg (95% CI: −1.03, −0.05) and 0.22 mmHg (95% CI: −0.59, 0.15) decrease in SBP and DBP, respectively. When using PM2.5exposures from fixed stations, the decrease in SBP and DBP were 0.95 mmHg (95% CI: −1.82, −0.07) and 0.74 mmHg (95% CI: −1.46, −0.03). Stratified analysis showed stronger effects in the central urban area and among males.ConclusionsBoth personal PM2.5exposure and exposure from fixed stations averaged over the previous 1 to 3 days decreased blood pressure. Stronger effects were found in a central urban area and among males.