Cued spatial attention drives functionally relevant modulation of the mu rhythm in primary somatosensory cortex.
Cued spatial attention drives functionally relevant modulation of the mu rhythm in primary somatosensory cortex.
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DOI：
10.1523/jneurosci.2969-10.2010
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发表时间：
2010-10-13
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影响因子：
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通讯作者：
Moore CI
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文献类型：
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作者：
Jones SR;Kerr CE;Wan Q;Pritchett DL;Hämäläinen M;Moore CI
提示空间注意调节人类视觉皮层中功能相关的α节律。在这里，我们提出了类似的现象在初级躯体感觉新皮层（SI）的证据。使用脑磁图（MEG），我们测量了SI μ节律的变化，其中包含μ-α（7-14 Hz）和μ-β（15-29 Hz）成分。我们发现，提示性注意影响了SI中躯体定位手表征中的μ-α，显示了将注意力提示到手后的功率下降和将注意力提示到脚后的功率增加，在提示后500-1100毫秒（ms）观察到显著差异。Mu-beta在提示后800- 850 ms的时间窗口中显示出差异。视觉提示还驱动早期诱发反应，其在提示后约70 ms开始，具有用提示注意调制的明显峰值。触觉刺激诱发反应的不同组成部分也调制与线索的注意。对第二个数据集的分析表明，在逐个试验的基础上，触觉检测概率随刺激前μ-α和μ-β功率线性下降。这些结果支持了越来越多的共识，提示诱导的α调制是一个功能相关的感觉门控机制部署的注意。此外，虽然提示注意有一个较弱的影响分配的μ-β，在这个波段的振荡也预测触觉检测。
Cued spatial attention modulates functionally relevant alpha rhythms in visual cortices in humans. Here, we present evidence for analogous phenomena in primary somatosensory neocortex (SI). Using magnetoencephalography (MEG), we measured changes in the SI mu rhythm containing mu-alpha (7-14 Hz) and mu-beta (15-29 Hz) components. We found that cued attention impacted mu-alpha in the somatopically localized hand representation in SI, showing decreased power after attention was cued to the hand and increased power after attention was cued to the foot, with significant differences observed 500-1100 milliseconds (ms) post-cue. Mu-beta showed differences in a time window 800–850ms post-cue. The visual cue also drove an early evoked response beginning ~70ms post-cue with distinct peaks modulated with cued attention. Distinct components of the tactile stimulus-evoked response were also modulated with cued attention. Analysis of a second data set showed that, on a trial-by-trial basis, tactile detection probabilities decreased linearly with pre-stimulus mu-alpha and mu-beta power. These results support the growing consensus that cue-induced alpha modulation is a functionally relevant sensory gating mechanism deployed by attention. Further, while cued attention had a weaker effect on the allocation of mu-beta, oscillations in this band also predicted tactile detection.