Development of a compact MRI system for trabecular bone volume fraction measurements

Development of a compact MRI system for trabecular bone volume fraction measurements
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DOI:
10.1002/mrm.20135
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发表时间:
2004-08-01
影响因子:
3.3
通讯作者:
Tsuzaki, T
Tsuzaki, T
中科院分区:
医学3区
文献类型:
--
作者:
Kose, K;Matsuda, Y;Tsuzaki, T

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利用0.21T永磁体和便携式MRI控制台,研制了一种用于测量跟骨骨小梁体积分数(TBVF)的紧凑型MRI系统。整个系统重量< 600 kg,安装在2 m x 2 m的空间内。使用外部参考体模(总测量时间= 5分钟)采集的足跟的两个横截面自旋回波图像来量化跟骨的TBVF。测量的线性和再现性通过质子密度调节的phantomy进行了评价。对健康女性志愿者进行定量超声(QUS)测量,结果显示TBVF与声速(SOS)之间存在较高的正相关(R-2 = 0.4539,0.2693)。这些结果证明了这种新系统用于测量骨密度的潜力。
A compact MRI system for measuring trabecular bone volume fraction (TBVF) of the calcaneus was developed with the use of a 0.21 T permanent magnet and portable MRI console. The entire system weighed < 600 kg and was installed in a 2 m x 2 m space. Two cross-sectional spin-echo images of a heel acquired with external reference phantoms (total measurement time = 5 min) were used to quantify the TBVF of the calcaneus. The linearity and reproducibility of the measurements were evaluated by means of proton density-adjusted phantoms. Comparative measurements with quantitative ultrasound (QUS) in groups of healthy female volunteers showed a relatively high positive correlation (R-2 = 0.4539,0.2693) between TBVF and the speed of sound (SOS). These results demonstrate the potential of this new system for measuring bone density.