Twin Registries: An Ongoing Success Story
Twin Registries: An Ongoing Success Story
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双胞胎注册：一个持续的成功故事
DOI：
10.1375/183242706779462714
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发表时间：
2006
影响因子：
0.9
通讯作者：
Y. Hur
中科院分区：
文献类型：
--
作者：
A. Busjahn;Y. Hur
申请一项双胞胎遗传和联系研究的资助，理由是“双胞胎研究是一种过时的方法，没有科学价值，如果有的话，只能在不知名的期刊上发表……”无论是《双胞胎研究与人类遗传学》，还是本期特刊作者引用的任何其他同行评议期刊，都不能用“晦涩”这个词。双胞胎研究并没有“过时”，而是证明了它在研究人类基因和环境的复杂相互作用方面越来越有价值；PubMed在1990年列出了713个“双胞胎”条目，这个数字在1995年、2000年和2005年分别增加到723、979和1126。双胞胎研究的基本要求之一是获得双胞胎，而双胞胎登记，而不是在“每个研究”的基础上自发招募，是实现这一目标的方法。2002年，该杂志专门为这一主题专门出版了一期专刊，并介绍了他们的招募策略、表型重点和对未来研究和合作的展望。该问题的目的不仅仅是作为注册表目录，而是鼓励其他人启动或扩展双集合，而不必“重新发明轮子”。自2002年以来，全球已经取得了重大进展。此外，双登记越来越多地涉及各个科学领域，从而产生了创新的研究项目。本期特刊介绍了使用双胞胎登记的各种研究领域，从产前到成年年龄，我们相信，这将对未来的科学进步做出重大贡献。2002年列出了36个登记处，而在这一期中，这一数字已增加到52个。我们感谢贡献者精心准备的手稿，展示了最近和新颖的发现以及刺激的信息和见解。此外，我们非常感谢美国国家环境健康科学研究所（NIEHS）的资助，没有他们，本期特刊就不可能出版。我们也感谢一些作者，他们贡献或支付整版费用来帮助我们支付本期的费用。最后，我们感谢尼克·马丁鼓励我们制作这一期，以及玛丽莎·格里默的专业编辑支持。我们希望这期特刊将成为各科学领域研究人员的有用资源，并促进国际合作，以解决有关人类疾病和生物行为特征的重要研究问题。
grant application for a twin heritability and linkage study on the grounds that ‘twin studies were an outdated methodology with no scientific merit, publishable only in obscure journals if anything ...’. Neither Twin Research and Human Genetics nor any of the other peer-reviewed journals cited by the authors of this special issue warrants the term ‘obscure’. Rather than being ‘outdated’, twin research has proven its increasing value for studying the complex interplay of genes and environment in humans; PubMed lists 713 entries for ‘twins’ for 1990, this number increasing to 723, 979 and 1126 in 1995, 2000 and 2005, respectively. One of the fundamental requirements for twin studies is access to twins, and twin registries, rather than spontaneous recruitment on a ‘per study’ basis, is the way to achieve this. In 2002 this journal devoted a full special issue to this topic, and established as well as newly emerging twin registries presented their recruitment strategies, phenotyping focus and their visions for future research and collaborations. The purpose of that issue was not just to serve as a directory of registries but was to encourage others to start or extend twin collections without having to ‘reinvent the wheel’. Since 2002, significant progress has been made around the globe. New twin registries have emerged in countries including Chile, Israel, Spain, and Taiwan, while others have been founded in the United States (US) and Europe, reflecting the worldwide acceptance of the twin registry as a valuable resource for scientific research. In addition, twin registries have been increasingly involved in various fields of science, resulting in the creation of innovative research projects. This special issue introduces a variety of research areas using registries of twins, ranging from prenatal to adulthood in age, which, we believe, will significantly contribute to the future advance of science. Whereas 36 registries were listed in 2002, the number has increased to 52 in this issue. We are grateful to the contributors for well-prepared manuscripts, presenting recent and novel findings and stimulating information and insights. In addition we are most appreciative of funding from the US National Institute of Environmental Health Sciences (NIEHS) without which this special issue would not have been possible. We also thank a number of authors who made contributions or paid full-page charges to help cover our expenses for this issue. Finally, we thank Nick Martin who encouraged us to produce this issue, and Marisa Grimmer for her expert editorial support. We hope that this special issue will serve as a useful resource for researchers from various scientific fields and facilitate international collaborations for the resolution of important research questions on human diseases and biobehavioral traits.