New fluorescent zinc complexes: towards specific sensors for hydrogen sulfide in solution
New fluorescent zinc complexes: towards specific sensors for hydrogen sulfide in solution
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DOI：
10.1039/b907115f
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发表时间：
2009-01-01
影响因子：
4
通讯作者：
Artaud, Isabelle
中科院分区：
文献类型：
--
作者：
Galardon, Erwan;Tomas, Alain;Artaud, Isabelle
通过配合物Tp（Ph，Me）Zn（OH）与7-羟基-4-甲基香豆素（MUH）或7-巯基-4-甲基香豆素（MUSH）反应，合成了两种新的荧光锌配合物1和2。虽然醇合衍生物TpPh，MeZn（MU）1对于感测硫化氢不是有效的，但是硫醇合络合物Tp（Ph，Me）Zn（MUS）2是比色“开启”和荧光“关闭”传感器，其在另外的硫醇如半胱氨酸或谷胱甘肽的存在下显示出对硫化氢的高选择性。
Two new fluorescent zinc complexes 1 and 2 have been synthesized by reaction of the complex Tp(Ph,Me)Zn(OH) with 7-hydroxy-4-methylcoumarin (MUH) or 7-mercapto-4-methylcoumarin (MUSH). While the alcoholato derivative TpPh, MeZn(MU) 1 is not efficient for sensing hydrogen sulfide, the thiolato complex Tp(Ph,Me)Zn(MUS) 2 is a colorimetric "turn-on" and fluorescence "turn-off" sensor which shows high selectivity for hydrogen sulfide in the presence of additional thiols like cysteine or glutathione.