CATABOLIC REPRESSION OF BACTERIAL SPORULATION
CATABOLIC REPRESSION OF BACTERIAL SPORULATION
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DOI：
10.1073/pnas.54.3.704
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发表时间：
1965-01-01
影响因子：
11.1
通讯作者：
AUBERT, JP
中科院分区：
文献类型：
--
作者：
SCHAEFFER, P;MILLET, J;AUBERT, JP
在基本培养基中呈指数生长的枯草芽孢杆菌培养物中，孢子和活细胞的数量以相同的速率增加;但孢子与细胞的比例取决于培养基的组成。在给定的培养基中，这个比值可以用来计算细菌形成孢子而不是繁殖的概率。该数学表达式可以反映一些含N分解代谢物的细胞内浓度，因为它取决于培养基中存在的C和N源的性质。这种催化剂可能作为至少一种孢子形成特异性酶的阻遏物，该酶可能是蛋白酶。
In cultures of Bacillus subtilis growing exponentially in minimal media, the numbers of spores and viable cells increase at the same rate; but the spore-to-cell ratio depends on the composition of the medium. In a given medium the value of this ratio can be used to calculate the probability with which a bacterium will sporulate rather than multiply. This mathematical expression may reflect the intra- cellular concentration of some N-containing catabolite(s), as it depends on the nature of both the C and N source present in the medium. Such catabolites probably act as repressors of at least 1 sporulation-specific enzyme, which might be a protease.