Toward an understanding of the neural mechanisms underlying dual-task performance: Contribution of comparative approaches using animal models
Toward an understanding of the neural mechanisms underlying dual-task performance: Contribution of comparative approaches using animal models
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DOI：
10.1016/j.neubiorev.2017.08.008
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发表时间：
2018
影响因子：
8.2
通讯作者：
Kei Watanabe;S. Funahashi
中科院分区：
文献类型：
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作者：
Kei Watanabe;S. Funahashi
人类双重任务绩效的研究在认知神经科学中引起了极大的兴趣，因为它可以提供对高阶认知控制的神经机制的详细见解。尽管经过了几十年的研究，但我们对双重任务绩效的神经生物学基础的了解仍然有限，一些关键问题仍在争论中。最近，对动物双重任务表现的行为和神经生理学研究已经开始提供有趣的证据，说明双重任务信息是如何在大脑中处理的。在这篇综述中，我们首先总结了人类神经影像和神经心理学研究中的关键证据，并讨论了不同研究之间存在差异的可能原因。然后，我们对动物双任务研究的文献进行了全面的综述，并提出了一个新的工作假说，该假说可能会协调人类研究中的不同结果，从而对双任务加工的机制有一个统一的看法。最后，我们在比较认知神经科学的框架下提出了未来双任务实验的可能方向。
The study of dual-task performance in human subjects has received considerable interest in cognitive neuroscience because it can provide detailed insights into the neural mechanisms underlying higher-order cognitive control. Despite many decades of research, our understanding of the neurobiological basis of dual-task performance is still limited, and some critical questions are still under debate. Recently, behavioral and neurophysiological studies of dual-task performance in animals have begun to provide intriguing evidence regarding how dual-task information is processed in the brain. In this review, we first summarize key evidence in neuroimaging and neuropsychological studies in humans and discuss possible reasons for discrepancies across studies. We then provide a comprehensive review of the literature on dual-task studies in animals and provide a novel working hypothesis that may reconcile the divergent results in human studies toward a unified view of the mechanisms underlying dual-task processing. Finally, we propose possible directions for future dual-task experiments in the framework of comparative cognitive neuroscience.