IMPACT OF PREVIOUS ANTIMICROBIAL THERAPY ON THE ETIOLOGY AND OUTCOME OF VENTILATOR-ASSOCIATED PNEUMONIA
IMPACT OF PREVIOUS ANTIMICROBIAL THERAPY ON THE ETIOLOGY AND OUTCOME OF VENTILATOR-ASSOCIATED PNEUMONIA
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DOI：
10.1378/chest.104.4.1230
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发表时间：
1993-10-01
期刊：
影响因子：
9.6
通讯作者：
PRATS, G
中科院分区：
文献类型：
--
作者：
RELLO, J;AUSINA, V;PRATS, G
Objective: To define the influence of prior antibiotic use on the etiology and mortality of ventilator-associated pneumonia (VAP).Setting: A university hospital medical-surgical ICU.Design: Prospective clinical study.Methods: Over a 35-month period, we prospectively studied 129 consecutive episodes of VAP. Etiologic diagnosis was established using a protected specimen brush and quantitative culture techniques. We examined prognostic factors by univariate and multivariate analyses using a statistical software package (SPSS).Results: The rate of VAP caused by Gram-positive cocci or Haemophilus influenzae was statistically lower (p
