COVID-19 associated pulmonary aspergillosis

COVID-19 associated pulmonary aspergillosis
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新型冠状病毒肺炎相关肺曲霉病

DOI:
10.1111/myc.13096
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发表时间:
2020-05-15
期刊:
影响因子:
4.9
通讯作者:
Shimabukuro-Vornhagen, Alexander
Shimabukuro-Vornhagen, Alexander
中科院分区:
医学2区
文献类型:
--
作者:
Koehler, Philipp;Cornely, Oliver A.;Shimabukuro-Vornhagen, Alexander

文献摘要

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目的病毒感染引起的急性呼吸窘迫综合征(ARDS)患者易发生侵袭性曲霉菌病等继发性并发症。我们的研究评估了冠状病毒病19方法回顾性分析在德国科隆大学医院内科或外科重症监护室收治的所有COVID-19相关ARDS患者的病历,德国.结果COVID-19例中重度ARDS患者中5例合并侵袭性肺曲霉菌病因COVID-19引起的患者应考虑侵袭性肺曲霉菌病,并对呼吸道样本进行综合分析,以检测合并感染。
Objectives Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany.Methods A retrospective chart review of all patients with COVID-19 associated ARDS admitted to the medical or surgical intensive care unit at the University Hospital of Cologne, Cologne, Germany.Results COVID-19 associated invasive pulmonary aspergillosis was found in five of 19 consecutive critically ill patients with moderate to severe ARDS.Conclusion Clinicians caring for patients with ARDS due to COVID-19 should consider invasive pulmonary aspergillosis and subject respiratory samples to comprehensive analysis to detect co-infection.