Metallic taste from electrical and chemical stimulation
Metallic taste from electrical and chemical stimulation
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DOI：
10.1093/chemse/bji014
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发表时间：
2005-03-01
期刊：
影响因子：
3.5
通讯作者：
Kurtz, A
中科院分区：
文献类型：
--
作者：
Lawless, HT;Stevens, DA;Kurtz, A
三个系列的实验研究了金属盐溶液刺激和金属和电流刺激后金属味道报告的性质。为了用电刺激，制造了一个装置，由一个小电池组成，贴在一个塑料手柄上，阳极露出来，放置在舌头或口腔组织上。来自金属和电池的味道强度取决于电压，在真菌状乳头密集的区域更强烈。据报道，用硫酸亚铁溶液刺激、金属刺激和电刺激都能产生金属味。然而，与简单的自由选择标签相反，当“金属”这个词被嵌入到选择列表中时，关于金属味道的报告更频繁。当鼻子被阻塞时，硫酸亚铁的强度下降，与先前报道的后鼻气味减少一致。铜金属、双金属刺激（锌/铜）或小电池（1.5- 3v）引起的味觉强度不受鼻腔阻塞的影响。这种差异表明两种不同的机制唤起的金属味道报告，一个依赖于后鼻嗅觉和第二个介导的口腔化学感受器。
A series of three experiments investigated the nature of metallic taste reports after stimulation with solutions of metal salts and after stimulation with metals and electric currents. To stimulate with electricity, a device was fabricated consisting of a small battery affixed to a plastic handle with the anode side exposed for placement on the tongue or oral tissues. Intensity of taste from metals and batteries was dependent upon the voltage and was more robust in areas dense in fungiform papillae. Metallic taste was reported from stimulation with ferrous sulfate solutions, from metals and from electric stimuli. However, reports of metallic taste were more frequent when the word 'metallic' was presented embedded in a list of choices, as opposed to simple free-choice labeling. Intensity decreased for ferrous sulfate when the nose was occluded, consistent with a decrease in retronasal smell, as previously reported. Intensity of taste evoked by copper metal, bimetallic stimuli (zinc/copper) or small batteries (1.5-3 V) was not affected by nasal occlusion. This difference suggests two distinct mechanisms for evocation of metallic taste reports, one dependent upon retronasal smell and a second mediated by oral chemoreceptors.