Genes, race, and population: Avoiding a collision of categories

Genes, race, and population: Avoiding a collision of categories
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DOI:
10.2105/ajph.2005.067926
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发表时间:
2006-11-01
影响因子:
12.7
通讯作者:
Kahn, Jonathan
Kahn, Jonathan
中科院分区:
医学2区
文献类型:
--
作者:
Kahn, Jonathan

文献摘要

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一系列广泛的联邦授权对在生物医学研究、临床实践、产品开发和卫生政策中使用种族和族裔类别产生了深远的影响。目前关于在生物医学背景下适当使用种族和民族类别的讨论主要集中在个别研究人员的实践上。相比之下,我们的讨论侧重于生物医学专业人员的日常实践与联邦监管任务之间的关系。它借鉴了平等保护的法律原则,以超越此类辩论,并提出指导方针,以解决联邦法规所施加的结构性力量,这些法规规定如何在生物医学研究中使用有关种族和族裔的数据。它提供了一个框架,以管理使用现有联邦政府规定的种族和民族类别以及关于人类遗传变异的新科学发现所涉及的紧张关系。
A wide array of federal mandates have a profound impact on the use of racial and ethnic categories in biomedical research, clinical practice, product development, and health policy. Current discussions over the appropriate use of racial and ethnic categories in biomedical contexts have largely focused on the practices of individual researchers.By contrast, our discussion focuses on relations between the daily practices of biomedical professionals and federal regulatory mandates. It draws upon the legal doctrine of equal protection to move beyond such debates and to propose guidelines to address the structural forces imposed by federal regulations that mandate how data about race and ethnicity are used in biomedical research. It offers a framework to manage the tension involved in using existing federally mandated categories of race and ethnicity alongside new scientific findings about human genetic variation.