Batrachochytrium dendrobatidis.

Batrachochytrium dendrobatidis.
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Batrachochytrium dendrobatidis。

DOI:
10.1016/j.pt.2021.04.014
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发表时间:
2021
影响因子:
9.6
通讯作者:
Sewell TR
Sewell TR
中科院分区:
医学1区
文献类型:
--
作者:
Sewell TR

文献摘要

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Batrachochytrium dendrobatidis is a zoospore-forming aquatic fungus and the etiological agent of chytridiomycosis, a skin infection affecting all orders of amphibians. B. dendrobatidis emerged worldwide during the 20th century, causing a panzootic that has contributed to widespread declines in the abundance of at least 501 amphibian species and 90 presumed extinctions. The pathogen has a two-stage life cycle, whereby flagellate-motile zoospores seek out amphibians by means of chemotaxis before attaching, encysting, and developing intracellularly into zoosporangia, which gestate and discharge new zoospores. Factors leading to the onset of chytridiomycosis following exposure to zoospores are complex, consisting of biotic and abiotic components that influence host–pathogen interactions. This results in differing clinical outcomes within and amongst species that range from no or mild symptoms to death and declines.