Feasibility of nationwide birth registry control selection in the United States
Feasibility of nationwide birth registry control selection in the United States
复制标题
DOI：
10.1093/aje/kwm143
复制
发表时间：
2007-10-01
影响因子：
5
通讯作者：
Bunin, Greta R.
中科院分区：
文献类型：
--
作者：
Spector, Logan G.;Ross, Julie A.;Bunin, Greta R.
由于随机数字拨号在许多类型的研究中变得越来越不可行，因此需要替代的对照选择方法，特别是对于儿童癌症的研究。美国出生登记处是一个有吸引力的年轻对照儿童的来源，因为他们是基于人口的，提供人口统计学和妊娠数据的参与者与研究基地进行比较，并保持数据，使出生特征匹配。在本文中，作者描述了美国出生登记处发布足够信息的能力，以确定两项正在进行的肝母细胞瘤和婴儿白血病病例对照研究的潜在对照受试者。32个州的出生登记，其中75.8%的美国0-5岁的儿童居住在2004年，同意参加控制选择。大多数登记处都提供了足够的数据来跟踪参与者和描述非应答者的特征。这些结果表明，出生登记可用于选择控制罕见的儿童疾病的研究在全国范围内。
As random digit dialing becomes increasingly unfeasible for many types of studies, alternative methods for control selection are needed, especially for studies of childhood cancer. US birth registries are an appealing source of young control children because they are population based, provide demographic and pregnancy data for comparison of participants with the study base, and maintain data that enable matching on birth characteristics. Here the authors describe the ability of US birth registries to release information sufficient to locate potential control subjects for two ongoing case-control studies of hepatoblastoma and infant leukemia. The birth registries of 32 states, in which 75.8% of US children 0-5 years of age resided in 2004, agreed to participate in control selection. Data sufficient to track participants and to characterize nonrespondents were available from a majority of registries. These results suggest that birth registries may be used to select controls for studies of rare childhood diseases on a national scale.