Effect of high-calcium diet on urinary oxalate excretion in urinary stone formers.
Effect of high-calcium diet on urinary oxalate excretion in urinary stone formers.
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高钙饮食对尿路结石患者尿草酸排泄的影响。
DOI：
10.1159/000473449
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发表时间：
1988
期刊：
影响因子：
23.4
通讯作者：
J. Shimazaki
中科院分区：
文献类型：
--
作者：
T. Nakada;I. Sasagawa;H. Furuta;T. Katayama;J. Shimazaki
对85例特发性尿石症患者进行了轻度高钙饮食与常规钙饮食对尿钙排泄、尿草酸排泄、尿钙/肌酐比值、尿草酸/肌酐比值及结石形成概率的影响研究。在特发性高钙尿症患者中，摄入高钙饮食5-6天可降低（p <0.01-p <0.001）尿草酸排泄量、尿草酸/肌酐比值和PSF。在常规钙饮食下，给予60 mg/天磷酸吡哆醛3个月降低（p <0.05-p <0.01）尿草酸排泄，尿草酸/肌酐比值和特发性高钙尿症患者的PSF。从这些发现，轻度高钙饮食的摄入似乎是有益的，以减少尿草酸排泄和PSF的特发性高钙尿症患者。磷酸吡哆醛具有抑制特发性高钙尿症患者结石形成风险因素的所有特征。
The effect of mild high-calcium diet or regular-calcium diet on urinary calcium excretion, urinary oxalate excretion, urinary calcium/creatinine ratio, urinary oxalate/creatinine ratio, and the probability of being a stone former (PSF) were studied in 85 patients with idiopathic urolithiasis. Intake of high-calcium diet for 5-6 days reduced (p less than 0.01-p less than 0.001) urinary oxalate excretion, urinary oxalate/creatine ratio and PSF in patients with idiopathic hypercalciuria. Under the regular-calcium diet, administration of 60 mg/day of pyridoxal phosphate for 3 months lowered (p less than 0.05-p less than 0.01) urinary oxalate excretion, urinary oxalate/creatinine ratio and PSF in patients with idiopathic hypercalciuria alone. From these findings, intake of mild high-calcium diet appears to be beneficial to decrease the urinary oxalate excretion and PSF in patients with idiopathic hypercalciuria. Pyridoxal phosphate has all the features of suppressing such risk factors for stone formation in patients with idiopathic hypercalciuria.