How Menopause Symptoms and Attitude Impact Korean Women's Quality of Life After Adjuvant Treatment for Breast Cancer
How Menopause Symptoms and Attitude Impact Korean Women's Quality of Life After Adjuvant Treatment for Breast Cancer
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DOI：
10.1097/ncc.0000000000000448
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发表时间：
2017-11-01
期刊：
影响因子：
2.6
通讯作者：
Oh, Kyongok
中科院分区：
文献类型：
--
作者：
Gang, Moonhee;Jung, Mi Sook;Oh, Kyongok
背景资料：不同文化对绝经期的态度各不相同，并影响妇女的绝经期症状的经验，可能导致乳腺癌幸存者治疗后生活质量下降。目的：本研究的目的是探讨绝经症状和态度对诊断时绝经前乳腺癌幸存者健康相关生活质量的影响。研究方法：共有139名接受化疗的妇女/无内分泌治疗进行了评估与自我报告问卷的可靠性和有效性。进行分层回归，以评估更年期症状和态度对生活质量的影响，同时控制人口统计学特征。结果如下：总体而言，参与者认可了46种症状中的一半以上，大多数症状轻微，大多数人对更年期的态度不太积极。当控制与生活质量相关的人口统计学因素时，更多的绝经期症状和更多的消极态度显著预测生活质量较低（R-2= 26.1%）。大多数参与者在完成辅助化疗（有或没有他莫昔芬）后经历了从绝经前到绝经后的变化。结论：结果表明，更多的更年期症状和对更年期的消极态度可能会影响健康相关的生活质量相当大的化疗治疗的亚洲乳腺癌幸存者。对实践的影响：医疗保健专业人员应根据患者的社会文化背景，采用文化相关的观点，更好地了解更年期症状和态度对生活质量的影响。此外，这些发现有助于医疗保健专业人员以更明智的方式与亚洲客户沟通，并提供文化上适当和个性化的护理。
Background: Attitudes toward menopause vary across cultures and influence women's experiences of menopausal symptoms, possibly leading to reduced posttreatment quality of life in breast cancer survivors. Objective: The aim of this study is to examine the effects of menopausal symptoms and attitudes on health-related quality of life in breast cancer survivors who were premenopausal at the time of diagnosis. Methods: A total of 139 women receiving chemotherapy with/without endocrine therapy were assessed with self-report questionnaires of established reliability and validity. Hierarchical regression was conducted to assess the impact of menopausal symptoms and attitudes on quality of life, while controlling for demographic characteristics. Results: Overall, participants endorsed more than half of 46 symptoms, most at the level of mild symptoms, and most reported a less positive attitude toward menopause. Lower quality of life was significantly predicted by more menopausal symptoms endorsed and more negative attitudes when controlling for demographic factors associated with quality of life (R-2= 26.1%). Most participants experienced change from premenopause to postmenopause after the completion of adjuvant chemotherapy with or without tamoxifen. Conclusions: The results suggest that more menopausal symptoms and negative attitudes toward menopause may affect health-related quality of life considerably in chemotherapy-treated Asian breast cancer survivors. Implications for Practice: Healthcare professionals should develop a better understanding of the effects of menopausal symptoms and attitudes on quality of life by using a culturally relevant perspective based on patients' sociocultural backgrounds. Furthermore, these findings help healthcare professionals communicate with their Asian clients in a more informed way and provide culturally appropriate and individualized care.