Relearning face-name associations in early Alzheimer's disease
Relearning face-name associations in early Alzheimer's disease
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DOI：
10.1037//0894-4105.16.4.538
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发表时间：
2002-10-01
期刊：
影响因子：
2.4
通讯作者：
Hodges, JR
中科院分区：
文献类型：
--
作者：
Clare, L;Wilson, BA;Hodges, JR
克莱尔等人（1999，2000，2001）提供了基于无错误学习原则的认知康复干预在早期阿尔茨海默病（AD）中有效性的初步证据。本研究在对照试验中扩展了这些发现。12名符合可能AD标准的参与者，其简易精神状态检查分数为18或以上，接受了使用无错误学习范式的面名联想训练。训练产生了显着的组改善回忆的训练，但不是控制，项目。6个月后，在缺乏实践的情况下，收益基本保持不变。个体对干预的反应存在差异。结果没有根据药物状态而有所不同，干预对自我报告的幸福感没有不良影响，但更了解自己记忆困难的参与者取得了更好的结果。
Preliminary evidence for the effectiveness of cognitive rehabilitation interventions based on errorless learning principles in early-stage Alzheimer's disease (AD) was provided by Clare et al. (1999, 2000, 2001). The present study extends these findings in a controlled trial. Twelve participants meeting criteria for probable AD, with Mini-Mental State Examination scores of 18 or above, were trained in face-name associations using an errorless learning paradigm. Training produced a significant group improvement in recall of trained, but not control, items. Gains were largely maintained 6 months later, in the absence of practice. There were differences in individual response to intervention. Results did not differ according to medication status, and the intervention had no adverse effects on self-reported well-being, but participants who were more aware of their memory difficulties achieved better outcomes.