The methoxylation of N-formylpyrrolidine in a microfluidic electrolysis cell for routine synthesis
The methoxylation of N-formylpyrrolidine in a microfluidic electrolysis cell for routine synthesis
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DOI：
10.1016/j.electacta.2012.02.093
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发表时间：
2012-05-01
影响因子：
6.6
通讯作者：
Underwood, Toby J.
中科院分区：
文献类型：
--
作者：
Kuleshova, Jekaterina;Hill-Cousins, Joseph T.;Underwood, Toby J.
一个单通道微流控电解池正在开发的应用与其他常规微流控操作在实验室中已被应用于甲氧基化的N-甲酰吡咯烷。结果表明，在单程中可以实现非常高的转化率（>>90%），并且可以在优化条件下以良好的选择性每小时获得几克产物。(C)2012爱思唯尔有限公司保留所有权利。
A single channel microfluidic electrolysis cell being developed for application alongside other routine microfluidic operations in the laboratory has been applied to the methoxylation of N-formylpyrrolidine. It is shown that very high conversions (>>90%) in a single pass can be achieved and it is possible to obtain several grams of product per hour with a good selectivity in optimised conditions. (C) 2012 Elsevier Ltd. All rights reserved.