Hemodynamic Response of the Supplementary Motor Area during Locomotor Tasks with Upright versus Horizontal Postures in Humans.
Hemodynamic Response of the Supplementary Motor Area during Locomotor Tasks with Upright versus Horizontal Postures in Humans.
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DOI：
10.1155/2016/6168245
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发表时间：
2016
影响因子：
3.1
通讯作者：
Hara Y
中科院分区：
文献类型：
--
作者：
Yozu A;Obayashi S;Nakajima K;Hara Y
为了了解在人体运动过程中躯干姿势控制相关的皮质机制，我们研究了10名健康成年人四足和双足步态的辅助运动区（SMA）的血流动力学反应，使用功能性近红外光谱。受试者进行三个运动任务的姿势不稳定的程度不同的生物力学，即，手膝四足爬行（HKQuad任务），直立四足使用双边Lofstrand拐杖（UpQuad任务），和典型的直立两足（UpBi任务），在跑步机上。我们在任务期间测量了氧合血红蛋白（oxygenated hemoglobin，oxy-Hb）的浓度。在HKQuad任务中，SMA中的oxy-Hb显著降低，而在UpQuad任务中则增加。在UpBi任务期间没有观察到显著的反应。根据氧合血红蛋白反应的程度，我们将这些运动任务排序为UpQuad > UpBi > HKQuad。不同任务的顺序与任务的姿势不稳定性不一致。然而，氧-Hb时间过程的定性检查表明，直立姿势任务（峰-坪-槽模式的UpQuad和UpBi任务）和水平姿势任务（下坡模式的HKQuad任务）之间的氧-Hb波形模式不同。因此，SMA可能有助于控制躯干姿势伴随人类的自发运动。
To understand cortical mechanisms related to truncal posture control during human locomotion, we investigated hemodynamic responses in the supplementary motor area (SMA) with quadrupedal and bipedal gaits using functional near-infrared spectroscopy in 10 healthy adults. The subjects performed three locomotor tasks where the degree of postural instability varied biomechanically, namely, hand-knee quadrupedal crawling (HKQuad task), upright quadrupedalism using bilateral Lofstrand crutches (UpQuad task), and typical upright bipedalism (UpBi task), on a treadmill. We measured the concentration of oxygenated hemoglobin (oxy-Hb) during the tasks. The oxy-Hb significantly decreased in the SMA during the HKQuad task, whereas it increased during the UpQuad task. No significant responses were observed during the UpBi task. Based on the degree of oxy-Hb responses, we ranked these locomotor tasks as UpQuad > UpBi > HKQuad. The order of the different tasks did not correspond with postural instability of the tasks. However, qualitative inspection of oxy-Hb time courses showed that oxy-Hb waveform patterns differed between upright posture tasks (peak-plateau-trough pattern for the UpQuad and UpBi tasks) and horizontal posture task (downhill pattern for the HKQuad task). Thus, the SMA may contribute to the control of truncal posture accompanying locomotor movements in humans.