Role of the spinal trigeminal nucleus in the rat autonomic reflex
Role of the spinal trigeminal nucleus in the rat autonomic reflex
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DOI：
10.1016/j.archoralbio.2009.08.008
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发表时间：
2009-12-01
影响因子：
3
通讯作者：
Izumi, Hiroshi
中科院分区：
文献类型：
--
作者：
Koeda, Satoko;Ishii, Hisayoshi;Izumi, Hiroshi
本研究的目的是探讨脊髓三叉核（Vsp）的三个亚核（口核、内插核和尾核）在引发副交感神经和交感反射自主神经反应方面的区域差异。我们通过电刺激人工通气、尿素麻醉、颈部迷走神经交感神经切除的大鼠下唇血流量（LBF）和全身动脉血压（SABP）的变化。电刺激内插肌Vsp引起的LBF增加明显大于口、尾肌。虽然电刺激口肌引起的SABP增加远小于内插肌和尾肌，但Vsp刺激下的SABP增加在内插肌和尾肌之间没有显著差异。本研究结果表明，Vsp内插亚核的Vsp作为中继参与舌神经和Vsp诱发的躯体-自主反射。2009爱思唯尔有限公司版权所有。
The goal of the present study was to investigate the regional differences between the three subnuclei (oralis, interpolaris, and caudalis) of the spinal trigeminal nucleus (Vsp) in eliciting parasympathetic and sympathetic reflex autonomic responses. We evoked changes in lower lip blood flow (LBF) and systemic arterial blood pressure (SABP) by electrically stimulating these subnuclei in artificially ventilated, urethane-anaesthetised, cervically vago-sympathectomized rats. The LBF increases evoked by electrical stimulation of the Vsp at interpolaris were much larger than those at the sites of the oralis and caudalis. No significant difference in SABP increase was observed by Vsp stimulation between the interpolaris and caudalis, although the SABP increase evoked by electrical stimulation of the oralis was much smaller than in the interpolaris and caudalis. The present findings show that the Vsp at the interpolaris subnucleus of the Vsp participates as a relay in lingual nerve and Vsp-evoked somato-autonomic reflex. (C) 2009 Elsevier Ltd. All rights reserved.