Evaluation of computed tomography-guided parapharyngeal mass needle biopsy through mandibular notch for diagnosis of recurrent nasopharygeal carcinoma
Evaluation of computed tomography-guided parapharyngeal mass needle biopsy through mandibular notch for diagnosis of recurrent nasopharygeal carcinoma
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DOI：
10.4103/0973-1482.145887
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发表时间：
2014-11-01
影响因子：
1.3
通讯作者：
Jiang, Hao
中科院分区：
文献类型：
--
作者：
Jiang, Liming;Xu, Haimiao;Jiang, Hao
Objective: The aim was to evaluate the effectiveness of computed tomography (CT)-guided fine-needle aspiration biopsy (FNAB) from Mandibular notch and under the zygomatic arch for pathological diagnosis of recurrence nasopharyngeal carcinoma (NPC) after radiotherapy (AT).Materials and Methods: Between October 2007 and December 2013, 48 patients with suspected recurrent NPC underwent CT-guided FNAB. A modified coaxial technique was used in all cases, and multiple samples were obtained for histological studies.Results: We obtained a definite histological diagnosis with 87.5% (42/48) overall diagnostic accuracy. In 42 patients the needle aspirate confirmed a clinical suspicion of recurrent disease and the histologic finding was positive (10 cases of squamous cell carcinoma, 3 cases of adenocarcinoma, finding tumor cells tend to squamous cell carcinoma in 24 patients and undifferentiated carcinoma in 5 patients). In the six cases of no tumor seen" confirmation was made by clinical and imaging follow-up showing 2 tumor relapse and 4 fibrillation.Conclusion: CT-guided FNAB from Mandibular notch and under the zygomatic arch is a safe and accurate technique useful for pathological diagnosis of recurrence NPC after RT.
