Peridomestic Lyme Disease Prevention Results of a Population-Based Case-Control Study
Peridomestic Lyme Disease Prevention Results of a Population-Based Case-Control Study
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DOI：
10.1016/j.amepre.2009.04.026
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发表时间：
2009-09-01
影响因子：
5.5
通讯作者：
Heimer, Robert
中科院分区：
文献类型：
--
作者：
Connally, Neeta P.;Durante, Amanda J.;Heimer, Robert
目的：在康涅狄格州进行了一项为期32个月的前瞻性病例对照研究，以评估牙周病预防措施对莱姆病风险的影响。方法：该研究于2005年至2007年在康涅狄格州的24个疾病流行社区进行。在迁徙红斑发病前一个月，通过电话对受试者进行了访谈，使用了一份旨在引出疾病预防措施的问卷。对2008年的数据进行条件Logistic回归分析。结果：在2005年4月至2007年11月期间，共对364名莱姆病患者进行了访谈，其中349人(96%)与合适的对照组相匹配。在家中院子里呆36小时内检查扁虱对莱姆病有保护作用(OR=0.55；95%CI=0.32，0.94)。在院子里逗留后2小时内洗澡也有保护作用(OR=0.42；95%CI=0.23，0.78)。院子里任何类型或高度的栅栏，无论是否相连，都是保护性的(OR=0.54；95%CI=0.33，0.90)。没有其他景观修改或特征对莱姆病有明显的保护作用。结论：本研究的结果表明，在牙周炎风险较高的地区，实际活动，如检查院子里的扁虱和在院子里度过一段时间后洗澡，可能会降低莱姆病的风险。围栏似乎确实能防止感染，但其保护机制尚不清楚。《美国预防医学杂志》2009年；37(3)：201-206
Background: Peridomestic Lyme disease-prevention initiatives promote personal protection, landscape modification, and chemical control.Purpose: A 32-month prospective age- and neighborhood-matched case-control study was conducted in Connecticut to evaluate the effects of peridomestic prevention measures oil risk of Lyme disease.Methods: The Study was conducted in 24 disease-endemic Connecticut communities from 2005 to 2007. Subjects were interviewed by telephone using a questionnaire designed to elicit disease-prevention measures during the month prior to the case onset of erythema migrans. Data were analyzed in 2008 by conditional logistic regression. Potential confounders, Such as occupational/recreational exposures, were examined.Results: Between April 2005 and November 2007, interviews were conducted with 364 participants with Lyme disease, and 349 (96%) were matched with a suitable control. Checking for ticks within 36 hours of spending time in the yard at home was protective against Lyme disease (OR=0.55; 95% CI=0.32, 0.94). Bathing within 2 hours after spending time in the yard was also protective (OR=0.42; 95% CI=0.23, 0.78). Fencing of any type or height in the yard, whether it was contiguous or not, was protective (OR=0.54; 95% CI=0.33, 0.90). No other landscape modifications or features were significantly protective against Lyme disease.Conclusions: The results of this study suggest that practical activities such as checking for ticks and bathing after spending time in the yard may reduce the risk of Lyme disease in regions where peridomestic risk is high. Fencing did appear to protect against infection, but the mechanism of its protection is unclear. (Am J Prev Med 2009;37(3):201-206) (C) 2009 American Journal of Preventive Medicine