Reproductive biology: Do males rely on female hormones?

Reproductive biology: Do males rely on female hormones?
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DOI:
10.1038/37236
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发表时间:
1997
期刊:
影响因子:
64.8
通讯作者:
R. Sharpe
R. Sharpe
中科院分区:
综合性期刊1区
文献类型:
--
作者:
R. Sharpe

文献摘要

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根据一篇描述男性生殖道中女性荷尔蒙(雌激素)功能的论文,男性和女性之间的差异可能会越来越小。缺乏雌激素受体a基因的老鼠是不育的,这被证明是由于精子在睾丸中储存的过程中存在缺陷。通常,储存包括从精子周围吸收液体,但是,在基因敲除小鼠中,分泌更多的液体。所以女性荷尔蒙对男性的影响可能是广泛的。
The difference between men and women could be getting smaller, according to a paper that describes a function for female hormones (oestrogens) in the male reproductive tract. Mice that lack the gene for the a form of the oestrogen receptor are infertile, and this turns out to be due to a defect in the process by which sperm are prepared for storage in the testis. Usually, storage involves resorption of fluid from around the sperm, but, in the knockout mice, more fluid is secreted. So the effects of female hormones in males may actually be widespread.