Photoactivation of (p-methoxyphenyl)(trifluoromethyl)diazirine in the presence of phenolic reaction partners.
Photoactivation of (p-methoxyphenyl)(trifluoromethyl)diazirine in the presence of phenolic reaction partners.
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DOI：
10.1002/chem.201203479
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发表时间：
2013-05
期刊：
影响因子：
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通讯作者：
Björn Raimer;T. Lindel
中科院分区：
文献类型：
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作者：
Björn Raimer;T. Lindel
照亮你的化学反应！在苯酚和酪氨酸衍生物的等摩尔溶液的存在下照射3-（4-甲氧基苯基）-3-（三氟甲基）-3H-二氮杂环丙烷导致Friedel-Crafts烷基化（参见方案），这表明了开发用于化学生物学的“更清洁的”二氮杂环丙烷的策略。
Shine light on your chemistry! Irradiating 3-(4-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine in the presence of equimolar solutions of phenol and tyrosine derivatives leads to Friedel-Crafts alkylations (see scheme), which suggests a strategy for the development of "cleaner" diazirines for chemical biology.