OPIUM ALKALOIDS .7. ISOLATION OF A NEW BENZYLISOQUINOLINE ALKALOID . SYNTHESIS AND NMR STUDIES OF PAPAVEROLINE TRIMETHYL ETHERS
OPIUM ALKALOIDS .7. ISOLATION OF A NEW BENZYLISOQUINOLINE ALKALOID . SYNTHESIS AND NMR STUDIES OF PAPAVEROLINE TRIMETHYL ETHERS
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DOI：
10.1002/jps.2600570605
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发表时间：
1968-01-01
影响因子：
3.8
通讯作者：
HIRAI, K
中科院分区：
文献类型：
--
作者：
BROCHMAN.E;HIRAI, K
从鸦片中分离出一种新的酚性生物碱，命名为帕劳定。其光谱表征为1-（3[image]-羟基-4 [image]-甲氧基苄基）-6，7-二甲氧基异喹啉，并通过合成确认了结构。合成了另外3个罂粟碱三甲基醚，并对其核磁共振谱进行了研究。
A new phenolic alkaloid was isolated from opium and named palaudine. It was characterized spectroscopically as l-(3[image]-hydroxy-4[image]-methoxybenzyl)-6,7-dimethoxyisoquinoline and the structure confirmed by synthesis. The other 3 papaveroline trimethyl ethers were also synthesized and their nuclear magnetic spectra investigated.