The Anatomy of the Conduction System: Implications for the Clinical Cardiologist
The Anatomy of the Conduction System: Implications for the Clinical Cardiologist
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DOI：
10.1007/s12265-012-9433-0
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发表时间：
2013-04-01
影响因子：
3.4
通讯作者：
Moorman, Antoon F. M.
中科院分区：
文献类型：
--
作者：
Anderson, Robert H.;Boyett, Mark R.;Moorman, Antoon F. M.
自从组织学上专门化的心肌细胞的解剖学排列细节出现以来，仅仅过了100多年，心肌细胞负责心脏冲动的启动和传播。此后不久，建立了组织学标准，以允许其在尸检的人类心脏中的位置。这些标准保留了它们的价值，但现在可以通过分子和免疫组织化学发现来增强。这些新技术使我们对窦和房室结的位置和详细结构沿着房室传导轴有了进一步的了解。它们还揭示了特殊心肌的额外区域的存在，例如终末嵴的结旁区和房室环组织。相反，他们没有提供肺静脉袖是组织学特化的概念的支持，但确实提供了对流出道心动过速基质的见解。这篇文章是JCTR心脏解剖学特刊的一部分。
It is just over 100 years since details emerged of the anatomical arrangement of the histologically specialised cardiomyocytes responsible for initiation and propagation of the cardiac impulse. Shortly thereafter, histological criteria were established to permit their location in autopsied human hearts. These criteria retain their value, but can now be enhanced by molecular and immunohistochemical findings. The new techniques have advanced our knowledge of the location and detailed structure of the sinus and atrioventricular nodes, along with the atrioventricular conduction axis. They also reveal the presence of additional areas of specialised myocardium, such as the paranodal area of the terminal crest, and the atrioventricular ring tissues. In contrast, they offer no support for the notion that the pulmonary venous sleeves are histologically specialised, but do provide insights to the substrates for outflow tract tachycardias. This article is part of a JCTR special issue on Cardiac Anatomy.