A new virus in a spontaneous mammary tumor of a rhesus monkey.
A new virus in a spontaneous mammary tumor of a rhesus monkey.
复制标题
恒河猴自发乳腺肿瘤中的一种新病毒。
作者：
H. Chopra;M. M. Mason
本研究探讨了在一个8岁恒河猴自发性乳腺肿瘤中检测到的病毒颗粒的超微结构和发展。在肿瘤生长的3个月期间，进行了几次活检。肿瘤组织的薄切片电子显微镜检查显示2种类型的颗粒：1）胞浆内电子致密环形颗粒，2）具有外部单位膜和中央致密类核的细胞外颗粒。通过在细胞膜水平上的出芽过程重建了胞质内发育和病毒成熟。
This study investigated the ultrastructure and development of virus particles detected in a spontaneous mammary tumor of an 8 year old rhesus monkey. During a 3-month period of tumor growth, several biopsies were performed. Thin section electron microscopy of the tumor tissue revealed 2 types of particles: 1) an intracytoplasmic, electron-dense, ring-shaped particle, and 2) an extracellular particle with an outer unit membrane and a central dense nucleoid. The intracytoplasmic development and virus maturation by a process of budding at the level of the cell membrane was reconstructed.