Spin-echo T1-weighted Imaging of the Brain with Interleaved Acquisition and Presaturation Pulse at 3 T: A Feasibility Study Before Clinical Use
Spin-echo T1-weighted Imaging of the Brain with Interleaved Acquisition and Presaturation Pulse at 3 T: A Feasibility Study Before Clinical Use
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DOI：
10.1016/j.acra.2008.12.026
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发表时间：
2009-07-01
影响因子：
4.8
通讯作者：
Togashi, Kaori
中科院分区：
文献类型：
--
作者：
Kasahara, Seiko;Miki, Yukio;Togashi, Kaori
基本原理和目标。尽管自旋回波 (SE) 序列在脑成像中比梯度回波序列具有一些优势，但梯度回波序列通常用于 3 T 的 T1 加权成像 (T1WI)，因为人们普遍认为 SE T1WI 的对比度在 3 T 时较差。最近，据报道，具有层间间隙的单层和多层 SE 成像的灰白质对比度在 3 T 时比 1.5 T 时更好。本研究检验了交错 SE 的可行性大脑在 3 T 时的 T1WI。本研究还检查了预饱和脉冲 (PP) 是否足以抑制动脉内信号，因为这些信号由于 3 T 时 T1 较长而往往呈高信号。材料和方法。受试者包括 18 名健康志愿者。使用SE序列进行两组T1WI。一组包括不使用 PP 的成像，另一组包括使用 PP 的成像。每组包含以下三种类型的无间隙成像；顺序、100% 交错和 200% 交错成像。对每个受试者的灰质和白质之间的对比度噪声比 (CNRGM-WM) 以及动脉内信号进行了评估。结果。无论 PP 如何，交错图像上的 CNRGM-WM 显着高于连续图像上的 CNRGM-WM (P < .0001)。 PP 充分抑制了动脉内信号 (P < .0001)。结论。 CNRGM-WM On SE T1WI at 3 T 可以通过交错采集得到改善，并且 PP 充分抑制了动脉内信号。交错 SE T1WI 与 PP 在 3 T 下似乎在临床上可行。
Rationale and Objectives. Although spin-echo (SE) sequence has some advantages over gradient-echo sequence in brain imaging, gradient-echo sequence is commonly used For T1-weighted imaging (T1WI) at 3 T because contrast on SE T1WI is widely believed to be poor at 3 T. Recently, gray-white matter contrast on single-slice and multi-slice SE imaging with interslice gap was reported as better at 3 T than at 1.5 T. This Study examined the feasibility of interleaved SE T1WI of the brain at 3 T. This study also examined whether presaturation pulse (PP) sufficiently suppresses intra-arterial signals because these signals tend to be hyperintense due to longer T1 at 3 T.Materials and Methods. Subjects consisted of 18 healthy volunteers. Two sets of T1WI were performed using SE sequence. One set consisted of imaging without PP, and the other consisted of imaging with PP. Each set contained three types of gapless imaging as follows; sequential, 100% interleaved, and 200% interleaved imaging. In each subject, contrast-to-noise ratio between gray-matter and white-matter (CNRGM-WM) and intra-arterial signals were evaluated.Results. CNRGM-WM was significantly higher on interleaved images than on sequential images, regardless of PP (P < .0001). PP sufficiently suppressed intra-arterial signals (P < .0001).Conclusion. CNRGM-WM On SE T1WI at 3 T can be improved by interleaved acquisition, and PP sufficiently suppressed intra-arterial signals. Interleaved SE T1WI with PP appears clinically feasible at 3 T.