Nutritional profiles of Neisseria gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing.
Nutritional profiles of Neisseria gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing.
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化学成分确定的培养基中淋病奈瑟菌、脑膜炎奈瑟菌和乳酸奈瑟菌的营养状况以及淋球菌分型的生长要求的使用。
DOI：
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发表时间：
1973
影响因子：
6.4
通讯作者：
B. Catlin
中科院分区：
文献类型：
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作者：
B. Catlin
淋球菌以60 min传代，10小时内产生约5 × 108 cfu/ml，24小时超过109 cfu/ml。淋病、脑膜炎奈瑟菌和内酰胺奈瑟菌。每个物种都有一个独特的营养配置文件，用于区分和identifiedit. On一系列定义的媒体缺乏不同的化合物组，脑膜炎球菌是相对均匀的，在他们的生长反应，更有能力比其他物种的菌株生物合成。淋球菌表现出多样性的营养需求，74株被细分为13个不同的集群（auxotypes）的基础上，他们的生长模式的反应，焦磷酸硫胺素，硫胺素，脯氨酸，精氨酸，蛋氨酸，异亮氨酸，次黄嘌呤。这些结果表明，建立一个系统的可行性缺陷型临床分离的N。淋病
the gonococci multiplied with generation times 60 min, yielding about 5 x 108 cfu/ml within 10 hr and more than 109 cfu/ml by 24 hr. Defined agar media were used for investigation of the growth requirements of 146 strains of N. gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica. Each species has a distinctive nutritional profile that serves to differentiate and identify it. On a series of defined media lacking different groups of compounds, the meningococci were relatively homogeneous in their growth responses and were more competent biosynthetically than strains of the other species. Gonococci exhibited a diversity of nutritional requirements; 74 strains were subdivided into 13 distinct clusters (auxotypes) on the basis of their patterns of growth responses to thiamine pyrophosphate, thiamine, proline, arginine, methionine, isoleucine, and hypoxanthine. Such results demonstrate the feasibility of developing a system for auxotyping of clinical isolates of N. gonorrhoeae.