Apoptotic and non-apoptotic caspase functions in neural development
Apoptotic and non-apoptotic caspase functions in neural development
复制标题
神经发育中的凋亡和非凋亡 caspase 功能
DOI:
10.1007/s11064-010-0341-x
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发表时间:
2011
期刊:
影响因子:
--
通讯作者:
M.
中科院分区:
文献类型:
--
作者:
Miura;M.
During neural development, massive cell death occurs in both vertebrates and invertebrates. Caspase is a central player in apoptosis that is evolutionally conserved. Genetic manipulation of the caspase activity inDrosophilaand mice has revealed that caspases control cell fate through apoptotic and non-apoptotic mechanisms, to ensure appropriate cell differentiation and maturation in the developing nervous system.