Effect of immobilization of the knee joint on mechanoreceptors in anterior cruciate ligament of the rabbit
Effect of immobilization of the knee joint on mechanoreceptors in anterior cruciate ligament of the rabbit
复制标题
膝关节固定对家兔前十字韧带机械感受器的影响
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
H. Uemura
中科院分区：
文献类型：
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作者：
Y. Michinaka;Hiroshi Yamamoto;Teruhiko Kawakami Yutaka Morisawa;H. Uemura
本实验观察了机械感受器在兔膝关节前交叉韧带的形态分布及膝关节制动对机械感受器的影响，并对膝关节恢复运动后机械感受器的形态学变化进行了定性和定量分析。与未固定对照侧的机械感受器数量相比，4周固定后机械感受器的总数无显著差异。然而，有一个非典型形态的Pacinian小体和Ruffini受体显着增加。当固定6周时，与对照组相比，机械感受器（包括典型和非典型机械感受器）的总数显着减少。再动员12周和24周后，机械感受器总数恢复到与对照侧无显著差异的水平，但典型机械感受器仍显著减少，非典型机械感受器增加。这些结果表明，制动带来的形态变化和机械感受器的数量减少。再动员后机械感受器总数恢复，但典型机械感受器不恢复，非典型机械感受器数量增加。这些变化被认为是不可逆转的。
We investigated the morphologic distribution of mechanoreceptors in the anterior cruciate ligament of the knee in rabbits and the effects of immobilization of the knee joint, and evaluated the qualitative and quantitative morphologic changes of the mechanoreceptors after resumption of movement of the knee joint. There was no significant difference in the total number of mechanoreceptors present after 4-week immobilization compared with the number of mechanoreceptors on the unfixed control side. However, there was a significant increase in Pacinian corpuscles and Ruffini receptors with an atypical morphology. When immobilization was performed for 6 weeks, the total number of mechanoreceptors, including typical and atypical ones, showed a significant decrease compared to the control. After 12 and 24 weeks of remobilization, the total number of mechanoreceptors had returned to a level not significantly different from that on the control side, but typical mechanoreceptors were still significantly decreased and the atypical mechanoreceptors had increased. These results suggest that immobilization brings about morphologic changes and a reduction in the number of mechanoreceptors. The total number of mechanoreceptors recovers after re-mobilization, but the typical mechanoreceptors do not return, and the number of atypical mechanoreceptors increas. These changes are thought to be irreversible.
DOI：
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发表时间：
1992
期刊：
The Journal of bone and joint surgery. American volume
影响因子：
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作者：
O'Connor,BL;Visco,DM;Brandt,KD;Myers,SL;Kalasinski,LA
通讯作者：
Kalasinski,LA